Adenylate cyclase responses to sucrose stimulation in membranes of pig circumvallate taste papillae
Michael Naima, Tal Ronena, Benjamin J. Striema, Martha Levinsona and Uri Zehavia
a Department of Biochemistry and Human Nutrition, Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot 76100, Israel
Comparative Biochemistry and Physiology Part B
Volume 100, Issue 3, 1991, Pages 455-458
Received 15 May 1991.
Available online 3 February 2003.
Abstract
Typical adenylate cyclase (AC) responses to guanine nucleotides were found in membranes of pig circumvallates (CV) taste papillae. Sucrose stimulated AC activity in the CV membranes and this stimulation was GTP dependent and tissue specific. The stimulatory effect of sucrose in the CV membranes was dependent on the concentration of membranes used in the AC assay. This study provides the first biochemical data on cellular transduction of taste in the pig, compares positively to preliminary results in cattle and supports recent suggestions for a role of cAMP in sweet taste transduction.
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